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One experiment posited that Sermorelin may increase mean nocturnal GH release by approximately 100%, GH peak amplitude by 33.3%, and 12-hour GH levels by approximately 82.5%, suggesting an immediate response

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Francesco Puppi, recent podium finisher of the Western States 100, wrote a thoughtful piece about the state of drug testing in ultras following the high profile test failure of Joyline Chepngeno in 2025

Since then, it's commonly used in treatment protocols